Saturday, June 24, 2017

By Kevin Graham


When one is dependent on opioids, withdrawal can start simply hours after taking one's last dose. One may experience diarrhea, vomiting, insomnia, restlessness, or muscle and bone pain. In the majority of cases, the biggest withdrawal symptoms are worst by seventy-two hours and eventually subside over the next 5 to 7 days. Generally, the physicians have to careful with the opioid dosing to avoid addiction and other consequences.

Opioids are compounds like morphine, opium, and heroin which cause alteration in the way the human mind perceives the world as well as altered sensations like the well-known feeling of being on top of the world. Among the most sought after effects of opioids (a misuse) are the hallucinogenic effects.

However, naltrexone is used mainly as a drug that acts to control alcohol dependence and addiction. This action of naltrexone occurs in high doses. Low dose naltrexone is used to treat a number of illnesses including Crohn's disease, multiple sclerosis (MS) and fibromyalgia. Whilst some degree of extensive research into the effect of the drug and Crohn's disease has been done, the use of this drug on multiple sclerosis and fibromyalgia still need much investigation.

Research shows narcotic use is higher among the less educated and unemployed. A recent report in the American Journal of Medicine specifically looked at fibromyalgia patients receiving opioids for their pain. There was an increased incidence of unemployment, disability payments, and history of substance abuse. Also, the statistics showed overall lower education and an increased incidence of unstable psychiatric disorders. The study was not small and contained over 450 patients, so the results were most likely valid despite potential statistical variances.

OIH typically produces diffuse pain, which often extends to regions that were not painful before. OIH tends to mimic opiated withdrawal with some of its symptoms along with increased pain. Additionally, if the patient is dealing with tolerance, an increase in dose would lessen the pain. This does not happen with OIH, in fact, the pain would be worsened.

In addition to relieving physical pain, opioids diminish emotional pain. One may find they are taking the prescriptions for anxiety, irritability, fear, or depression. Studies have shown that the rate of major depression is directly related to how much pain a person feels. The more pain experienced, the higher the depression symptoms.

Induction is a treatment which carefully is followed by the center's clinical staff to slowly assist a new patient in adjusting to their methadone medicine. Patients typically are started on a safe methadone dose which introduces a low threat of overdose, and their dose then is increased every couple of days until the individual arrives at a dosage that successfully eliminates their withdrawal symptoms to opioids.

A tolerance will develop as the body gets used to methadone treatment that will require methadone users to consume higher doses to experience their high. As very high doses don't offer the same effects, users are going to move forward with harder drugs.

By blending drugs, abusers will risk overdose and dangerous interactions. Permitting this harmful experimentation encourages and enables addiction. If someone you love or yourself is abusing methadone, quit before you cause further harm.




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